Related Experiment Video
Updated: Feb 20, 2026
05:34
Applying Cheminformatics to Develop a Structure Searchable Database of Analytical Methods
Published on: June 6, 2025
1.7K
Expanding the chemical information science gateway
1Department of Life Science Informatics, B-IT, LIMES Program Unit Chemical Biology and Medicinal Chemistry, Rheinische Friedrich-Wilhelms-Universität, Bonn, Germany.
F1000Research
|October 19, 2017
Summary
Chemical Information Science (CIS) encompasses chemical data analysis and information retrieval. The Chemical Information Science Gateway (CISG) offers an open-access platform for innovative research in this interdisciplinary field.
Area of Science:
- Chemical Information Science (CIS) is an interdisciplinary field.
- It involves chemical structure and data analysis, including biological activity.
- CIS also covers the processing, organization, and retrieval of chemical information.
Background:
- The Chemical Information Science Gateway (CISG) on F1000Research was established to disseminate research across the chemical information spectrum.
- CISG serves as a venue for high-quality publications, offering an alternative to traditional journals.
- It is backed by experts advocating for open science and flexible publishing.
Discussion:
- This editorial clarifies the scope of CISG and its place within the scientific landscape.
- It aims to broaden the audience for CISG publications.
- The interdisciplinary nature of CIS allows for integration with experimental work.
Key Insights:
- CISG provides a dedicated platform for chem(o)informatics and related research.
- The gateway supports open science principles and flexible publication models.
- It encourages contributions that may be considered unconventional.
Outlook:
- CISG is positioned to foster interdisciplinary connections, particularly with experimental sciences.
- The platform aims to increase the visibility and accessibility of chemical information science research.
- Future contributions are expected to expand the reach of CISG within the scientific community.
Related Concept Videos
01:27Inductive Effects on Chemical Shift: Overview
2.3K
The protons in unsubstituted alkanes are strongly shielded with chemical shifts below 1.8 ppm. Methine, methylene, and methyl protons appear at approximately 1.7, 1.2 and 0.7 ppm, while the proton signal from methane appears at 0.23 ppm. An electronegative substituent, such as chlorine, withdraws the electron density from the protons, increasing their chemical shift. Progressive substitution of the hydrogens in methane by chlorine shifts the proton signals increasingly downfield, to 3.05 ppm in...
2.3K
01:09Chemical Symbols
122.7K
A chemical symbol is an abbreviation that is used to indicate an element or an atom of an element. For example, the symbol for mercury is Hg. We use the same symbol to indicate one atom of mercury (microscopic domain) or to label a container of many atoms of the element mercury (macroscopic domain).
Some symbols are derived from the common name of the element; others are abbreviations of the name in another language. Most symbols have one or two letters, but three-letter symbols have been used...
Some symbols are derived from the common name of the element; others are abbreviations of the name in another language. Most symbols have one or two letters, but three-letter symbols have been used...
122.7K
01:17Chemical Shift: Internal References and Solvent Effects
1.4K
In an NMR sample, precise measurement of the absolute absorption frequencies of nuclei is difficult. A standard internal reference compound is added, and the frequency difference between the reference signal and sample signals is measured.
The internal reference compound generally used in NMR spectroscopy is tetramethylsilane (TMS). TMS is preferred because it is chemically inert, soluble in NMR solvents, and easily removable. Also, the highly shielded methyl protons in TMS yield an intense...
The internal reference compound generally used in NMR spectroscopy is tetramethylsilane (TMS). TMS is preferred because it is chemically inert, soluble in NMR solvents, and easily removable. Also, the highly shielded methyl protons in TMS yield an intense...
1.4K
02:21Chemical and Solubility Equilibria
5.1K
The free energy change associated with dissolving a solute in a liter of solvent is called the free energy of a solution, ΔGsolution. The overall ΔGsolution is expressed as the balance of ΔGinteraction against the always-favorable free-energy of mixing, ΔGmixing. Solution formation is favorable if ΔGsolution is less than zero, whereas it is unfavorable if ΔGsolution is greater than zero. In short, for a solution to form and complete dissolution to take place,...
5.1K
01:27Effects of Chemicals: Overview
2.3K
Drugs, encompassing various chemical compounds from natural sources, lab synthesis, or genetic engineering, elicit different biological responses in living organisms. Some of these responses are desirable or therapeutic, while others are undesirable. The primary goal of administering a drug is to achieve a therapeutic effect, that is, to address a specific disease or health condition. Any concurrent effects outside of this therapeutic outcome are considered undesirable. These undesirable...
2.3K
01:26Chemical Synapses
12.0K
Chemical synapses are specialized sites between two neurons or between a neuron and a non-neuronal cell like a muscle, glandular or sensory cell.
Because chemical synapses depend on the release of neurotransmitter molecules from synaptic vesicles to pass on their signal, there is an approximately one millisecond delay between when the axon potential reaches the presynaptic terminal and when the neurotransmitter leads to opening of postsynaptic ion channels. Additionally, this signaling is...
Because chemical synapses depend on the release of neurotransmitter molecules from synaptic vesicles to pass on their signal, there is an approximately one millisecond delay between when the axon potential reaches the presynaptic terminal and when the neurotransmitter leads to opening of postsynaptic ion channels. Additionally, this signaling is...
12.0K