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Updated: Feb 20, 2026

Murine Bilateral Renal Lymphadenectomy
Published on: December 30, 2025
Primary renal lymphoma: an unusual finding following radical nephrectomy
Cody M Rissman1, Lawrence M Dagrosa2, Jason R Pettus2
1Dartmouth - Geisel School of Medicine, Hanover, and.
Abstract:
Secondary kidney involvement by disseminated non-Hodgkin's lymphoma (NHL) is quite common and is estimated to approach 30 - 60% in NHL patients. However, primary renal lymphoma is exceedingly rare and estimated to make up less than 1% of all kidney masses. We report a case of primary renal NHL presenting with profound hypercalcemia and renal failure recalcitrant to medical management, ultimately treated with urgent radical nephrectomy. To our knowledge, this is the first report of primary renal lymphoma presenting in this acute fashion.
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