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Updated: Feb 20, 2026

Mouse Kidney Transplantation: Models of Allograft Rejection
Published on: October 11, 2014
Acquired cystic kidney disease in allograft with long-standing poor function
Leonardo Cardili1, Henrique Machado de Sousa Proença2, Marcello Fabiano de Franco1
1Universidade Federal de São Paulo.
Abstract:
Acquired Cystic Kidney Disease (ACKD) is regarded as a common late condition of end stage renal damage and expresses its most important features when associated with long term hemodialysis. ACKD is also widely known as a premalignant lesion. Its occurrence in chronically rejected renal allografts is rare and its frequency and behavior in this setting are not well known. Herein we report a case of ACKD in a long standing nonfunctional allograft (215 months) which is not associated with malignancy and briefly review the related literature.
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