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Updated: Feb 20, 2026
09:09
Description of a Swine Infant Model of Volume-Controlled Hemorrhagic Shock
Published on: November 3, 2023
1.5K
[Diffuse alveolar hemorrhage in 4 girls]
Jia-Jia Dai1, Qiang Chen, Li-Bo Wang
1Children's Hospital of Fudan University, Shanghai 201102, China. ja666@163.com.
Summary
Bronchial artery to pulmonary circulation shunt (BPS) is a rare condition in children presenting with recurrent cough and anemia. Transcatheter embolization effectively treated these symptoms, offering a new therapeutic avenue.
Area of Science:
- Pediatric Pulmonology
- Interventional Radiology
- Rare Diseases
Background:
- Recurrent cough and anemia in children can mimic idiopathic pulmonary hemosiderosis.
- Idiopathic pulmonary hemosiderosis is often treated with corticosteroids.
Observation:
- Four young girls presented with recurrent cough, anemia, and shortness of breath.
- Bronchoalveolar lavage fluid tested positive for hemosiderin; imaging showed ground-glass opacity or interstitial changes.
- Patients unresponsive to idiopathic pulmonary hemosiderosis treatment were investigated further.
Findings:
- Selective bronchial arteriography revealed bronchial artery to pulmonary circulation shunt (BPS) in all four girls.
- Transcatheter embolization was performed to correct the abnormal shunts.
- A six-month follow-up showed no recurrence of cough and anemia.
Implications:
- Bronchial artery to pulmonary circulation shunt (BPS) should be considered in pediatric cases of unexplained recurrent cough and anemia, especially those refractory to corticosteroid therapy.
- Transcatheter embolization is a successful treatment for BPS in children.
- Early diagnosis and intervention for BPS can prevent persistent respiratory and hematological symptoms.
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