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Simplified Whole Body Plethysmography to Characterize Lung Function During Respiratory Melioidosis
Published on: February 24, 2023
Melioidosis: the great mimicker
Mandeep Singh1, Mehvish Mahmood1
1Department of Internal Medicine, San Joaquin General Hospital, French Camp, USA.
Abstract:
Melioidosis is an infectious disease endemic in Northern Australia and South East Asia. It is associated with high degrees of morbidity and mortality. On average, around five cases are diagnosed annually in the USA. Diagnosis remains a challenge, as it mimics many other conditions, especially tuberculosis, hence its other name, the 'great mimicker.' The present case involves a recent traveler to the Philippines, who presented with episodic fevers and weight loss to his primary care physician. Blood cultures ordered grew Burkholderia pseudomallei. Primary care physicians should suspect melioidosis in symptomatic patients with travel history to endemic areas.
Insights
Melioidosis, a serious infectious disease, is often misdiagnosed due to its varied symptoms. Early suspicion in travelers returning from endemic areas is crucial for timely Burkholderia pseudomallei diagnosis.
Area of Science:
- Infectious Diseases
- Microbiology
- Global Health
Background:
- Melioidosis is a significant infectious disease prevalent in Northern Australia and Southeast Asia.
- It is characterized by high morbidity and mortality rates.
- Approximately five cases are diagnosed annually in the USA.
Observation:
- The diagnosis of melioidosis presents a challenge due to its resemblance to other conditions, notably tuberculosis.
- A case study involved a traveler returning from the Philippines presenting with fever and weight loss.
- Blood cultures identified Burkholderia pseudomallei.
Findings:
- Burkholderia pseudomallei is the causative agent of melioidosis.
- The bacterium thrives in endemic regions and can cause severe illness.
- Prompt identification is key to effective treatment.
Implications:
- Primary care physicians should consider melioidosis in patients with relevant travel history and suggestive symptoms.
- Increased awareness can improve early diagnosis and patient outcomes.
- Further research into diagnostic methods and treatment protocols is warranted.
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