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Related Concept Videos

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Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
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Related Experiment Video

Updated: Feb 20, 2026

Lensless On-chip Imaging of Cells Provides a New Tool for High-throughput Cell-Biology and Medical Diagnostics
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Lensless photography with only an image sensor.

Ganghun Kim, Kyle Isaacson, Rachael Palmer

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    |October 20, 2017
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    Summary
    This summary is machine-generated.

    Researchers demonstrate a novel optical imaging technique using a bare complementary metal-oxide-semiconductor (CMOS) sensor and computational reconstruction. This breakthrough could enable new camera designs without traditional optics.

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    Area of Science:

    • Optics and Photonics
    • Computational Imaging
    • Sensor Technology

    Background:

    • Traditional photography relies on optics and image sensors.
    • Eliminating optics presents opportunities for novel camera form factors.

    Purpose of the Study:

    • To demonstrate a computational imaging technique using a bare CMOS sensor without optics.
    • To explore the feasibility of optical imaging through space-variant point-spread functions.

    Main Methods:

    • Utilized a bare CMOS sensor to capture images based on space-variant point-spread functions.
    • Employed a reconstruction algorithm to form images from sensor data.
    • Tested imaging of LED arrays and LCD screens, extending to video.

    Main Results:

    • Successfully imaged simple objects using the bare sensor and computational reconstruction.
    • Demonstrated the extension of the technique to video imaging.
    • Analyzed the impact of object distance on imaging performance.

    Conclusions:

    • Computational imaging with bare sensors is feasible, offering a path to opticless cameras.
    • Further improvements in sensor design and reconstruction algorithms can enhance this technology.
    • This approach holds potential for developing compact and innovative imaging devices.