Related Experiment Video

Updated: Feb 20, 2026

Large-Scale Purification of Porcine or Bovine Photoreceptor Outer Segments for Phagocytosis Assays on Retinal Pigment Epithelial Cells
10:02

Large-Scale Purification of Porcine or Bovine Photoreceptor Outer Segments for Phagocytosis Assays on Retinal Pigment Epithelial Cells

Published on: December 12, 2014

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BBSome function is required for both the morphogenesis and maintenance of the photoreceptor outer segment

Ying Hsu1,2, Janelle E Garrison2, Gunhee Kim2

  • 1Interdisciplinary Graduate Program in Molecular Medicine, University of Iowa, Iowa City, Iowa, United States.

Plos Genetics
|October 20, 2017
PubMed
Summary

Restoring Bardet-Biedl syndrome protein 8 (BBS8) in developing mouse retinas can reverse outer segment defects, restoring normal vision. This suggests a critical window for therapeutic intervention in inherited retinal diseases.

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