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Patterns of Prostate-Specific Antigen Test Use in the U.S., 2005-2015
Zahava Berkowitz1, Jun Li1, Thomas B Richards1
1Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia.
American Journal of Preventive Medicine
|October 21, 2017
Summary
Prostate-specific antigen (PSA) testing decreased in men aged 55-69 but remained high in older men. Despite recommendations, PSA screening patterns show little change for key age groups.
Area of Science:
- Urology
- Public Health
- Epidemiology
Background:
- Prostate-specific antigen (PSA) screening recommendations increasingly focus on men aged 55-69.
- Understanding population-based PSA testing patterns is crucial for guiding screening strategies.
Purpose of the Study:
- To describe trends in PSA testing among different age groups, with a focus on men aged 55-69.
- To analyze PSA testing patterns by age and risk factors (African American men, family history).
Main Methods:
- Analysis of National Health Interview Survey data from 2005-2015.
- Estimation of routine PSA testing rates in men aged 40-54, 55-69, and ≥70 years.
- Logistic regression models used to assess changes over time by age and risk groups.
Main Results:
- PSA testing in men aged 55-69 decreased from 43.1% in 2008 to 33.8% in 2015.
- Men aged ≥70 years showed consistently high PSA testing prevalence across survey years.
- A 5% absolute decrease in PSA testing was observed across risk groups, significant only in 'other' men.
Conclusions:
- The absolute decrease in PSA testing for men aged 55-69 was modest (9.3%) despite observed trends.
- High PSA testing prevalence persists in men aged ≥70, a group where benefits may not outweigh harms.
