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Updated: Feb 20, 2026

Generation and Culture of Lingual Organoids Derived from Adult Mouse Taste Stem Cells
Published on: April 5, 2021
Unlocking the Complex Flavors of Dysgeusia after Hematopoietic Cell Transplantation
Michael Scordo1, Gunjan L Shah1, Jonathan U Peled1
1Adult BMT Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College, New York, New York.
Abstract:
Dysgeusia is a frequently occurring symptom after hematopoietic cell transplantation (HCT) that has important long-term effects on physical, nutritional, and immunologic recovery, as well as on quality of life. Despite the relevance of this symptom, the study of dysgeusia in patients undergoing HCT has been limited, owing in part to its complexity. In this article, we review normal taste function and its clinical evaluation, discuss how dysgeusia uniquely affects patients undergoing HCT, and examine distinct, transplantation-related contributors to dysgeusia that may help elucidate strategies to ultimately reduce this symptom burden after transplantation.
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