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Published on: September 5, 2013
Draft Genome Sequences of One Methicillin-Sensitive and Seven Methicillin-Resistant Staphylococcus aureus Sequence
Samantha J Hau1, Darrell O Bayles2, David P Alt2
1Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA.
Abstract:
Staphylococcus aureus is a commensal bacterium of humans that can cause a spectrum of diseases. An isolate's capacity to cause disease is partially attributed to the acquisition of novel mobile genetic elements. This report provides the draft genome sequence of one methicillin-susceptible and seven methicillin-resistant clinical human S. aureus isolates.
Insights
This study presents the draft genome sequences of eight clinical Staphylococcus aureus isolates. Understanding these genomes aids in studying how these bacteria cause disease.
Area of Science:
- Microbiology
- Genomics
- Bacterial Pathogenesis
Background:
- Staphylococcus aureus is a common human bacterium.
- Mobile genetic elements contribute to S. aureus's disease-causing potential.
- Understanding bacterial genomes is crucial for disease research.
Purpose of the Study:
- To provide draft genome sequences for clinical Staphylococcus aureus isolates.
- To support research into the genetic basis of S. aureus pathogenicity.
Main Methods:
- Whole-genome sequencing of clinical S. aureus isolates.
- Bioinformatic analysis of generated genome data.
Main Results:
- Draft genome sequences were generated for eight clinical S. aureus isolates.
- Sequences included one methicillin-susceptible and seven methicillin-resistant strains.
Conclusions:
- The generated genome sequences provide valuable resources for studying S. aureus.
- Further research can utilize these genomes to investigate virulence factors and antibiotic resistance mechanisms.
