Myocardial remodelling and recovery in dilated cardiomyopathy
Upasana Tayal1,2, Sanjay K Prasad1,2
1National Heart Lung Institute, Imperial College London, UK.
JRSM Cardiovascular Disease
|October 21, 2017
Insights
Myocardial reverse remodeling occurs in many dilated cardiomyopathy patients. This review explores recovery potential, prognostic impact, and predictors of this cardiac healing.
Area of Science:
- Cardiology
- Cardiovascular Medicine
Background:
- Myocardial reverse remodeling is observed in 25-70% of dilated cardiomyopathy patients.
- The nature of this remodeling (remission vs. cure) and the capacity for recovery remain unclear.
Purpose of the Study:
- To review the potential for recovery in dilated cardiomyopathy (DCM).
- To discuss the prognostic implications of myocardial recovery.
- To identify clinical and imaging predictors of myocardial remodeling.
Main Methods:
- Literature review of studies on dilated cardiomyopathy and myocardial reverse remodeling.
- Analysis of existing data on recovery capacity, prognosis, and predictors.
Main Results:
- Dilated cardiomyopathy patients exhibit a significant capacity for myocardial reverse remodeling.
- The prognostic significance of this recovery is variable and requires further investigation.
- Several clinical and imaging markers may predict the potential for myocardial remodeling.
Conclusions:
- Understanding the capacity for recovery in DCM is crucial for patient management.
- Further research is needed to clarify the long-term implications of reverse remodeling.
- Identifying predictors can guide therapeutic strategies and improve patient outcomes.
Abstract:
Myocardial reverse remodeling has been reported to occur in 25-70% of patients with dilated cardiomyopathy. It is not yet fully understood whether remodeling represents disease remission or cure and which hearts retain this capacity to recover. In this review article we discuss the capacity for recovery in DCM, the prognostic implications of this recovery and potential clinical and imaging predictors for myocardial remodeling.
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