Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Postmenopausal endometrial patterns and serum estradiol concentrations.

A A Ismail1, M Ramadan, A Soliman

  • 1Department of Gynaecology, Alexandria University, Egypt.

International Journal of Gynaecology and Obstetrics: the Official Organ of the International Federation of Gynaecology and Obstetrics
|August 1, 1988
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparative effects of tannic acid and ZnO nanoparticles on hydration, microstructure, and antimicrobial performance of Portland cement.

RSC advances·2026
Same author

Synthesis, structural characterization, and dual DNA/HSA binding of novel Palladium(II) violurate complex with selective p53/Caspase-3-mediated anticancer activity.

Scientific reports·2026
Same author

Impact of hydrotalcite phases on the texture characteristic of OPC and its correlation with compressive strength and gamma Attenuation.

Scientific reports·2026
Same author

Synergistic impact of mesoporous Zn/Al-LDH nanorods for developing dielectric and thermal properties of epoxy as insulation in GIS/GIL.

Scientific reports·2026
Same author

Dynamic allele usage of X-linked genes ameliorates neurodevelopmental disease phenotypes in brain organoids.

Nature communications·2026
Same author

Evaluating the impact of housing modifications on milk infrared spectra as indicators of dairy cow welfare status.

Scientific reports·2025

Serum estradiol (E2) levels can help screen for postmenopausal endometrial hyperplasia and malignancy. Elevated E2 was linked to higher risks of these conditions in women undergoing endometrial biopsy.

Area of Science:

  • Reproductive Endocrinology
  • Gynecologic Oncology

Background:

  • Postmenopausal uterine bleeding requires accurate diagnosis.
  • Endometrial biopsy is standard but can be inadequate.
  • Serum estradiol (E2) levels may offer a non-invasive screening method.

Purpose of the Study:

  • To investigate the correlation between serum estradiol levels and endometrial patterns in postmenopausal women.
  • To evaluate the utility of serum E2 as a screening tool for endometrial hyperplasia and malignancy.

Main Methods:

  • Endometrial biopsy was performed on 80 postmenopausal women.
  • Serum estradiol (E2) levels were measured.
  • Correlation analysis between E2 levels and endometrial histology was conducted for 50 women with adequate biopsies.

Related Experiment Videos

Main Results:

  • Proliferative endometrium was the most common finding.
  • Endometrial malignancy was found in 15.8% of women with uterine bleeding.
  • Significantly elevated serum E2 levels were observed in women with malignant endometrium or adenomatous hyperplasia compared to those with other endometrial patterns.

Conclusions:

  • Serum estradiol measurement is a recommended, simple screening test for detecting postmenopausal endometrial hyperplasia and/or malignancy.
  • Elevated serum E2 may indicate an increased risk of significant endometrial pathology in postmenopausal women.