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Population genetics of the globin genes in Polynesians
R J Trent1, K N Mickleson, J Yakas
1Molecular Biology Laboratory, University of Sydney, NSW, Australia.
Hemoglobin
|January 1, 1988
Abstract:
Globin gene mapping data enable Polynesians to be divided into three distinct groups: (i) Maoris, Cook Islanders, (ii) Tongans, Samoans, (iii) Niue Islanders. Unusual RFLPs detected by the restriction enzymes Apa I and Bgl II are found in Polynesians. A high frequency of alpha-thalassemia in this population is explained by genetic drift and a founder effect.