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Association between male pattern baldness and prostate disease: A meta-analysis
Tao Jin1, Tao Wu2, Zhumei Luo3
1Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, China.
Urologic Oncology
|October 22, 2017
Summary
Male pattern baldness (MPB) is linked to a higher risk of prostate cancer (PC) and benign prostatic hyperplasia (BPH). This meta-analysis confirms these associations, highlighting the importance of further research into these conditions.
Area of Science:
- Andrology
- Urology
- Dermatology
Background:
- Male pattern baldness (MPB) has been anecdotally linked to increased risks of prostate cancer (PC) and benign prostatic hyperplasia (BPH).
- The precise nature and strength of these associations require quantitative evaluation.
Purpose of the Study:
- To conduct a meta-analysis to quantitatively assess the risk of PC and BPH in individuals experiencing MPB.
- To determine the statistical significance of the association between MPB and these prostatic conditions.
Main Methods:
- A systematic literature search was performed across multiple scientific databases.
- Pooled odds ratios (OR) and 95% confidence intervals (CIs) were calculated to synthesize data from eligible studies.
Main Results:
- The meta-analysis included 17 studies with 68,448 participants.
- MPB was significantly associated with an increased risk of aggressive PC (OR = 1.59) and BPH (OR = 1.26).
- Vertex baldness showed a statistically significant association with PC (OR = 1.18), but no significant link was found with BPH for vertex or frontal plus vertex patterns.
Conclusions:
- MPB is associated with an elevated risk for both PC and BPH.
- Further research, particularly prospective cohort studies, is recommended to solidify these findings and advance understanding.
- The findings underscore the potential link between androgenetic alopecia and prostatic health.
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