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Updated: Feb 20, 2026

Fine-tuning the Size and Minimizing the Noise of Solid-state Nanopores

Fine-tuning the Size and Minimizing the Noise of Solid-state Nanopores

Published on: October 31, 2013

Active sieving across driven nanopores for tunable selectivity.

Sophie Marbach¹, Lydéric Bocquet¹

¹Laboratoire de Physique Statistique, UMR CNRS 8550, Ecole Normale Supérieure, PSL Research University, 24 Rue Lhomond, 75005 Paris, France.

The Journal of Chemical Physics

|October 23, 2017

Summary

This summary is machine-generated.

Active sieving using externally driven nanopores significantly enhances molecular separation compared to traditional passive methods. This novel approach offers dynamic control over filtration and osmotic pressure, promising advancements in separation technologies.

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Area of Science:

Physical Chemistry
Materials Science
Nanotechnology

Background:

Traditional molecular separation relies on passive nanoporous membranes.
Limitations exist in achieving high selectivity and dynamic control with passive systems.

Purpose of the Study:

To explore the theoretical concept of non-equilibrium active sieving.
To investigate the separation capabilities of an active noisy nanopore with externally driven gating.

Main Methods:

Theoretical modeling of an active noisy nanopore.
Analytical and numerical analysis of gating frequency effects on separation.
Investigation of size and charge-based gating mechanisms.

Main Results:

A rich sieving diagram was revealed based on forced gating frequency.
Active sieving demonstrated significantly increased separation ability compared to passive sieving.
Dynamic tuning of osmotic pressure was shown to be feasible.

Conclusions:

Active sieving outperforms passive sieving for molecular separation.
Externally driven nanopore gating offers enhanced control and efficiency.
This approach presents a promising direction for advanced filtration technologies.