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In Vitro Model of Human Cutaneous Hypertrophic Scarring using Macromolecular Crowding
Published on: May 1, 2020
Use of polymethylmethacrylate (PMMA) microspheres collagen to treat atrophic acne scars
Qin Xiang Ng1, Shawn Shao Hong Koh2, Dongju Shin3
1Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.
Abstract:
Acne scarring is a common and persistent sequela affecting many individuals worldwide, with significant physical and long-lasting psychological effects. Currently, the treatment options available for acne scars are mostly invasive and have several side effects. This paper explores the possibility of using polymethylmethacrylate (PMMA) collagen microspheres, a relatively underexplored technique hitherto, to treat common atrophic scars. PMMA-collagen is more popularly used in injectable wrinkle fillers. Preliminary research has shown that PMMA-collagen has a beneficial effect on atrophic scars while having the added advantage of being safe, tolerable and minimally invasive as well.

