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Author Spotlight: Assessing the Cardiovascular Profile of Patients with Metabolic Syndrome
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Elevated cardiovascular risk factors in multiple sclerosis.

Charly Keytsman1, Bert O Eijnde1, Dominique Hansen1

  • 1REVAL Rehabilitation Research Center, BIOMED Biomedical Research Institute, Faculty of Medicine and Life Sciences, Hasselt University, Agoralaan Building A, Diepenbeek, Belgium.

Multiple Sclerosis and Related Disorders
|October 23, 2017
PubMed
Summary
This summary is machine-generated.

Multiple sclerosis (MS) patients exhibit higher cardiovascular disease (CVD) risk factors, including elevated fat mass and blood pressure. Managing body fat is crucial for reducing CVD risk in MS.

Keywords:
Body compositionCardiovascular diseasesFat massMortalityMultiple sclerosis

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Area of Science:

  • Cardiovascular Health
  • Neurology
  • Metabolic Health

Background:

  • Multiple sclerosis (MS) is linked to increased cardiovascular mortality.
  • Understanding cardiovascular disease (CVD) risk factors in MS is essential for prevention.

Observation:

  • MS patients showed significantly higher fat mass, fat percentage, systolic and diastolic blood pressure (BP), and resting heart rate (HR) compared to healthy controls.
  • Elevated blood triglycerides, fasting and 2-hour insulin, 2-hour glucose, and HOMA index were observed in MS patients.
  • No significant differences in total cholesterol, HDL, or LDL levels were found between MS patients and controls.

Findings:

  • MS is independently associated with increased fat mass/percentage, systolic and diastolic BP, and HR.
  • Fat mass in MS patients appears to be an independent contributor to other measured CVD risk factors.

Implications:

  • Individuals with MS have a heightened risk for CVD.
  • Reducing whole body fat should be a key component of managing MS treatment to mitigate cardiovascular risks.