Related Experiment Videos
[Animal models of tardive dyskinesia]
P J Bédard1, R Boucher, T DiPaolo
1Département d'Anatomie, Faculté de Médecine, Université Laval, Québec, Canada.
L'Encephale
|September 1, 1988
Abstract:
It is possible to induce in monkeys abnormal movements of the mouth and tongue resembling strikingly tardive dyskinesia. Such movements can be induced by chronic treatment with neuroleptics or by lesions placed in the habenular interpeduncular tract or nucleus parafascicularis thalami. Dopaminergic D1 and D2 receptors are involved in the modulation of such movements.