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Updated: Feb 20, 2026

Description of a Swine Infant Model of Volume-Controlled Hemorrhagic Shock
Published on: November 3, 2023
[Prevention postpartum hemorrhage]
Валерий Г Волков1, Елена М Гусева1
1ФГБОУ ВО "ТУЛЬСКИЙ ГОСУДАРСТВЕННЫЙ УНИВЕРСИТЕТ", ТУЛА, РОССИЯ.
Introduction:
Postpartum hemorrhage remains a leading cause of maternal morbidity and mortality.
The Aim:
To evaluate the effectiveness of oxytocin into the umbilical vein for the prevention of postpartum hemorrhage.
Materials And Methods:
A total of 105 women were included. Formed two groups. In group, I (n = 51) - as prevention of bleeding was administered oxytocin in the umbilical cord vein. In group, II (n = 54) 10 IU oxytocin was carried out by intramuscular injection in the thigh during the first minute after birth.
Results:
The duration of III stage of labor - 7,47 ± 1,39 minutes in group, I, 9,5 ± 1 minutes - in II (p>0,05). Pathology III stage of labor and the early postpartum period (placenta defect, tight attachment of the placenta, early hypo tonic bleeding) was observed in 9 (17,6%) in group, I and in 6 (11%) - II. Total blood loss during labor: in group, I - 57,19 ± 189 ml in the II - 221,6 ± 30,14 ml (p>0,05). In group, I, the mean hemoglobin content in peripheral blood before birth was 117 ± 2,55 g / l, in II - 123 ± 3,56 g / l (p>0,05). After birth, the average level of hemoglobin in the group, I was down to 112 ± 3,93 g / l, in II - up to 116 ± 3,46 g / l (p>0,05).
Conclusions:
The administration of oxytocin in the vein of the umbilical cord as a means of prevention of bleeding can be used to reduce the duration of the III stage of labor and the amount of blood loss.
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