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Updated: Feb 20, 2026

Assessment of Human Natural Killer Cell Events Driven by FcγRIIIa Engagement in the Presence of Therapeutic Antibodies
Published on: May 22, 2020
Fucoidans Stimulate Immune Reaction and Suppress Cancer Growth
Vaclav Vetvicka1, Jana Vetvickova2
1University of Louisville, Department of Pathology, Louisville, KY, U.S.A. vaclav.vetvicka@louisville.edu.
Background/Aim:
Fucoidans are gaining popularity as natural immunomodulators. The aim of this study was to compare the immunological activities or both purified samples and commercially available mixtures containing fucoidan.
Materials And Methods:
We evaluated the effects of various samples on phagocytosis, mitogenic response, natural killer (NK) activity, antibody formation and inhibition of breast cancer growth.
Results:
We found significant immunostimulating activity, but the strength of these effects was different among individual samples.
Conclusion:
Fucoidans have strong immunostimulating potential, including inhibition of cancer, with isolated samples offering better activity than commercial mixtures.
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