Related Experiment Video
Updated: Feb 20, 2026
Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
Corrected Cephalometric Analysis to Determine the Distance and Vector of Distraction Osteogenesis for Syndromic
Shinji Kobayashi1, Toshihiko Fukawa1, Takashi Hirakawa1
1Department of Plastic and Reconstructive Surgery, Kanagawa Children's Medical Center, Yokohama, Japan; Fukawa Orthodontic Office, Kamakura, Japan; Hirakawa Orthodontic Clinic, Yokohama, Japan; and Department of Plastic and Reconstructive Surgery, Yokohama City University Hospital, Yokohama, Japan.
Background:
The purpose of this study was to confirm the utility of a corrected cephalometric analysis to facilitate the planning of distraction osteogenesis with Le Fort III osteotomy for syndromic craniosynostosis.
Methods:
This prospective study involved 4 male and 2 female patients (mean patient age, 8 years 9 months; age range, 4 years 6 months to 13 years 2 months) with Crouzon syndrome who were treated with Le Fort III maxillary distraction using our previously described system of analysis of a corrected cephalogram and who underwent clinical follow-up. Lateral cephalograms were obtained immediately after device removal.
Results:
Distraction of orbitale moved the vector downward to the adult profile, but there was slightly less elongation than the adult profile for the distraction distance. The desired and real mean angles after distraction of point A were 29.2 ± 7.9° and 6.1 ± 8.5°, respectively, and the desired and the real mean distances after distraction of point A were 30.6 ± 12.7 mm and 29.4 ± 4.1 mm, respectively.
Conclusions:
Using the corrected cephalometric analysis, the distance and vector of distraction osteogenesis with Le Fort III osteotomy could be determined in patients with syndromic craniosynostosis. The distraction system brought the patients' facial bones to the planned position using controlling devices.
