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Related Experiment Video

Updated: Feb 20, 2026

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
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Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction

Published on: May 17, 2024

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Prepectoral Implant-Based Breast Reconstruction.

Lyndsey Highton1, Richard Johnson1, Cliona Kirwan1

  • 1Nightingale Breast Centre, University Hospital of South Manchester NHS Foundation Trust, United Kingdom.

Plastic and Reconstructive Surgery. Global Open
|October 25, 2017
PubMed
Summary
This summary is machine-generated.

Prepectoral implant breast reconstruction using acellular dermal matrices (ADMs) offers good cosmetic outcomes and patient satisfaction. This approach avoids pectoral muscle disruption, leading to quicker recovery with minimal complications.

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Area of Science:

  • Plastic Surgery
  • Reconstructive Surgery
  • Biomaterials in Medicine

Background:

  • Acellular dermal matrices (ADMs) have advanced single-stage implant breast reconstruction (IBR) after mastectomy.
  • Conventional postpectoral IBR with ADM improves aesthetics but may cause pain and muscle disruption.
  • This study investigates prepectoral IBR utilizing total ADM coverage.

Purpose of the Study:

  • To evaluate the outcomes of prepectoral implant breast reconstruction with total acellular dermal matrix coverage.
  • To assess patient satisfaction, cosmetic results, and complication rates associated with this technique.

Main Methods:

  • A prospective study of 106 patients (166 breasts) undergoing prepectoral IBR with total ADM coverage from 2013-2017.
  • Included immediate IBR and revision of submuscular IBR cases.
  • Analysis of patient demographics, surgical complications, and outcomes from a prospective database.

Main Results:

  • Good patient satisfaction and cosmetic outcomes at a mean follow-up of 485 days.
  • Low rates of complications: 8.4% minor (delayed healing, seroma) and 3% major (necrosis, implant loss).
  • No significant capsular contracture or animation deformity; no delays in adjuvant therapy.

Conclusions:

  • Prepectoral IBR with ADM cover is a viable alternative for breast reconstruction.
  • This technique provides good cosmetic results and facilitates rapid recovery without compromising pectoral muscle function.
  • It offers an alternative to traditional methods, minimizing associated muscle-related issues.