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Updated: Feb 20, 2026

Author Spotlight: A Non-Invasive Tool to Assess and Differentiate Fat Patterns in Liver Using 3D Dixon MRI
Published on: October 20, 2023
Fat-Containing Liver Lesions on Imaging: Detection and Differential Diagnosis
Andreu F Costa1, Seng Thipphavong2, Thomas Arnason3
11 Department of Diagnostic Radiology, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Victoria General Bldg, 3rd Fl, 1276 S Park St, Halifax, NS B3H 2Y9, Canada.
Objective:
The purpose of this article is to review how fat is detected on imaging and to discuss the differential diagnosis of fat-containing liver lesions.
Conclusion:
Fat is a highly useful feature in characterizing liver lesions on imaging. Although a variety of liver lesions can show fat on cross-sectional imaging, the presence of fat usually indicates that the lesion is of hepatocellular origin. Less commonly, nonhepatocellular fatty lesions may be distinguished by ancillary clinical and imaging features.
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