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Published on: November 14, 2025
Screening Mammography in Women 40-49 Years Old: Current Evidence
Kimberly M Ray1, Bonnie N Joe1, Rita I Freimanis1
11 Department of Radiology and Biomedical Imaging, University of California, San Francisco, 1600 Divisadero St, Box 1667, C-250, San Francisco, CA 94115.
Objective:
Breast cancer is an important health problem for women 40-49 years old, yet screening mammography for this age group remains controversial. This article reviews recent guidelines and supporting evidence on screening mammography in women of this age group.
Conclusion:
Evidence supports the benefit of annual screening mammography in women 40-49 years old. Models of different breast cancer screening strategies consistently show the greatest breast cancer mortality reduction and life-years gained with annual screening starting when women reach 40 years old.
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