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Updated: Feb 20, 2026

Author Spotlight: Overcoming Anti-VEGF Resistance Through Advanced Vascular Morphology Assessment in Choroidal Neovascularization
Published on: August 11, 2023
CLINICAL COURSE OF INFLAMMATORY CHOROIDAL NEOVASCULARIZATION ASSOCIATED WITH FOCAL CHOROIDAL EXCAVATION
Eleonora Corbelli1, Riccardo Sacconi1,2, Lea Querques1
1Department of Ophthalmology, University Vita-Salute, IRCCS Ospedale San Raffaele, Milan, Italy.
Purpose:
To report the clinical course of focal choroidal excavation associated with choroidal neovascularization in a case of choroidal inflammation.
Methods:
Case report.
Results:
A 41-year-old man presented with blurred vision and metamorphopsia in his left eye. Multimodal imaging including optical coherence tomography angiography showed nonconforming focal choroidal excavation in the setting of choroidal inflammation and the presence of choroidal neovascularization at the border of the excavation, nicely visualized by optical coherence tomography angiography. Pattern alteration from nonconforming to conforming focal choroidal excavation and choroidal neovascularization involution were observed after treatment with oral steroids.
Conclusion:
Multimodal imaging, including optical coherence tomography angiography, allowed to detect and monitor pattern focal choroidal excavation transformation and choroidal neovascularization reduction after treatment with oral steroids.
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