Related Experiment Video

Updated: Feb 20, 2026

E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy
06:28

E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy

Published on: August 1, 2019

9.3K

The Role of Bowel Preparation in Colorectal Surgery: Results of the 2012-2015 ACS-NSQIP Data

Aaron L Klinger1, Heather Green1, Dominique J Monlezun2

  • 1Department of Colon and Rectal Surgery, Ochsner Medical Center, New Orleans, LA and Ochsner Clinic School, University of Queensland School of Medicine, Brisbane, Queensland, Australia.

Annals of Surgery
|October 25, 2017
PubMed
Abstract

Insights

Combined mechanical and oral antibiotic bowel preparation significantly reduces infectious complications in colorectal surgery. This dual approach is recommended for elective procedures to lower risks of surgical site infections and anastomotic leaks.

Area of Science:

  • Colorectal surgery
  • Surgical infection prevention
  • Gastrointestinal surgery

Background:

  • Mechanical bowel preparation (MBP) and oral antibiotic bowel preparation (ABP) are used for colorectal resections, but their efficacy is debated.
  • Recent literature questions the benefit of MBP alone in reducing infection rates.
  • The use of ABP has a long history but remains controversial.

Purpose of the Study:

  • To evaluate the infectious complication rates associated with combined mechanical and oral antibiotic bowel preparation versus other preparation methods.
  • To determine the benefits of dual bowel preparation in elective colorectal surgery.

Main Methods:

  • Analysis of 27,804 patients from the 2012-2015 American College of Surgeons National Surgical Quality Improvement Program cohorts.
  • Utilized doubly robust propensity score-adjusted multivariable regression to assess complications.
  • Compared outcomes across four groups: no preparation, MBP only, ABP only, and combined MBP/ABP.

Main Results:

  • Combined MBP/ABP was associated with significantly lower rates of surgical site infection (SSI), organ space infection, wound dehiscence, and anastomotic leak compared to no preparation.
  • Dual preparation showed a lower SSI rate than ABP alone.
  • MBP monotherapy did not demonstrate significant benefits for infectious complications.

Conclusions:

  • Combined mechanical and oral antibiotic bowel preparation significantly reduces infectious complications, including SSI, organ space infection, wound dehiscence, and anastomotic leak.
  • This dual preparation strategy lowers infectious complication rates without increasing the risk of Clostridium difficile infection.
  • The study recommends combined MBP/ABP for elective colon and rectal resections when feasible.

More Related Videos

Surgical Robot-Assisted Transanal Specimen Extraction Radical Sigmoidectomy Without an Auxiliary Abdominal Incision07:22

Surgical Robot-Assisted Transanal Specimen Extraction Radical Sigmoidectomy Without an Auxiliary Abdominal Incision

Published on: June 13, 2025

1.0K
Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists03:43

Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists

Published on: July 11, 2025

819

Related Concept Videos

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy01:26

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
805
Endoscopic Procedures II: Colonoscopy01:25

Endoscopic Procedures II: Colonoscopy

The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:
820
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
731
Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy01:26

Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy

This lesson explores three gastrointestinal imaging techniques: radionuclide testing, colonic transit studies, and virtual colonoscopy.
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and...
462