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Related Experiment Video

Updated: Feb 20, 2026

Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing
07:13

Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing

Published on: October 20, 2021

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High-performance wireless powering for peripheral nerve neuromodulation systems.

Yuji Tanabe1, John S Ho2, Jiayin Liu3

  • 1Department of Electrical Engineering, Stanford University, Stanford, California 94305, United States of America.

Plos One
|October 25, 2017
PubMed
Summary
This summary is machine-generated.

This study presents a miniaturized wireless powering system for soft neuromodulation devices, achieving high performance for vagus nerve stimulation. This breakthrough enhances the clinical potential of bioelectronic therapies for various disorders.

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Area of Science:

  • Bioelectronic Medicine
  • Biomedical Engineering
  • Neuroscience

Background:

  • Neuromodulation using bioelectronic devices offers therapeutic potential for diverse disorders.
  • Long-term operation of these devices requires wireless powering, posing challenges for miniaturization and deep placement.

Purpose of the Study:

  • To develop and assess a miniaturized wireless powering system for soft neuromodulation devices.
  • To demonstrate high-performance wireless power transfer for in vivo vagus nerve stimulation.

Main Methods:

  • Miniaturized integration of a wireless powering system into a soft neuromodulation device (15 mm length, 2.7 mm diameter).
  • In vivo wireless stimulation of the vagus nerve in a porcine animal model.
  • Utilized a focused and circularly polarized field for enhanced power transfer efficiency.

Main Results:

  • Achieved high power transfer efficiency (approximately 10%) for the miniaturized device.
  • Demonstrated successful in vivo wireless stimulation of the vagus nerve.
  • The focused, circularly polarized field improved efficiency and polarization misalignment immunity.

Conclusions:

  • The developed wireless powering system shows significant clinical potential for neuromodulation therapies.
  • This technology addresses key challenges in miniaturized, deeply implanted bioelectronic devices.
  • Enhanced efficiency and robustness pave the way for advanced bioelectronic treatments.