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Open surgery for iliofemoral deep vein thrombosis with temporary arteriovenous fistula remains valuable
Markus U Wagenhäuser1,2, Hellai Sadat1, Philip Dueppers1
11 Department of Vascular and Endovascular Surgery, University Hospital of Düsseldorf, Düsseldorf, Germany.
Insights
Open surgical venous thrombectomy is a safe procedure for iliofemoral deep vein thrombosis, showing good long-term patency. However, it significantly impacts patients' physical, social, and mental quality of life.
Area of Science:
- Vascular Surgery
- Thrombosis Management
- Quality of Life Research
Background:
- Deep vein thrombosis (DVT) of the iliofemoral system can lead to significant morbidity.
- Post-thrombotic syndrome (PTS) is a common complication, impacting quality of life.
- Surgical venous thrombectomy is an alternative treatment option for selected DVT cases.
Purpose of the Study:
- To evaluate the outcomes of open surgical venous thrombectomy with a temporary arteriovenous fistula.
- To assess the procedure's impact on health-related quality of life (HRQoL) in patients with iliofemoral DVT.
Main Methods:
- Retrospective analysis of 48 patient medical records (26 long-term follow-up).
- Kaplan-Meier estimation for mortality, patency, and PTS rates.
- Statistical analysis of risk factors, coagulation disorders, and HRQoL.
Main Results:
- One-year survival rate: 93%.
- Primary one-year patency rate: 89%; secondary: 97%.
- Eight-year freedom from PTS: 80%; PTS rate: 20%.
- HRQoL was impaired in physical, social, and mental domains compared to normative data (p < .05).
Conclusions:
- Open surgical venous thrombectomy demonstrates favorable safety and patency outcomes compared to alternative treatments.
- Iliofemoral DVT significantly impairs patients' physical, social, and mental HRQoL.
- Surgical thrombectomy may be a viable option, but long-term quality of life deficits require attention.
Abstract:
Objective We assessed outcomes of open surgical venous thrombectomy with temporary arteriovenous fistula, and the procedure's effect on health-related quality of life. Method We retrospectively analyzed 48 (26 at long-term) patient medical records. Mortality rates, patency, and risk of post-thrombotic syndrome were analyzed using Kaplan-Meier estimation. The association between risk factors/coagulation disorders and patency/post-thrombotic syndrome along with patient health-related quality of life at long-term was analyzed employing various statistical methods. Results Patient one-year survival rate was 93 ± 4% and primary one-year patency rate was 89 ± 5% (secondary one-year patency rate 97 ± 3%). Freedom from post-thrombotic syndrome after eight years was 80 ± 12% (post-thrombotic syndrome rate 20 ± 12%). Health-related quality of life was impaired vs. normative data in the physical and social subscales, and in the mental component score ( p < .05). Conclusions Open surgical venous thrombectomy appears safe compared with literature-reported outcomes in similar patients using alternative approaches. Iliofemoral deep vein thrombosis impairs physical, social, and mental health-related quality of life.
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