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Related Concept Videos

Fatigue01:21

Fatigue

811
Fatigue occurs when materials rupture under repeated or fluctuating loads, even at stress levels far below their static breaking strength. It typically results in brittle failure, even for ductile materials. It is a critical consideration in designing machines and structural components subjected to repetitive or varying loads. The nature of these loadings can range from fluctuating loads like unbalanced pump impellers causing vibrations to repeatedly bending a thin steel rod wire back and forth...
811
Muscle Recovery and Fatigue01:24

Muscle Recovery and Fatigue

4.1K
Muscle fatigue refers to the decline in a muscle's ability to maintain the force of contraction after prolonged activity. It primarily stems from changes within muscle fibers. Even before experiencing muscle fatigue, one may feel tired and have the urge to stop the activity. This response, known as central fatigue, occurs due to changes in the central nervous system, namely the brain and spinal cord. While there is no single mechanism that induces fatigue, it may serve as a protective...
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Fatigue Strength of Concrete01:22

Fatigue Strength of Concrete

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Fatigue, in the context of materials science and engineering, refers to the weakening or failure of a material caused by repeatedly applied loads, even if these loads are below the strength limit of the material. Fatigue strength in concrete is a critical property that influences its durability and longevity. Concrete can fail in two ways due to fatigue. Static fatigue or creep rupture occurs under a constant load or one that increases slowly. The other failure mode is due to cyclical or...
553
Characteristics of Practical Op Amps01:16

Characteristics of Practical Op Amps

839
A difference amplifier, a crucial component in numerous electronic devices, ideally amplifies only the difference-mode signal, which is the difference between two input signals. However, in practical circuits, the output voltage depends on both the differential gain and the common-mode gain.
The ratio of differential gain to the common-mode gain is defined as the common-mode rejection ratio (CMRR). This ratio quantifies the ability of operational amplifiers (op-amps) to reject common-mode...
839
Theoretical Foundations of Nursing Practice01:30

Theoretical Foundations of Nursing Practice

17.3K
Theories play an essential role in organizing patient care. Theories refer to a proposed or followed belief, policy, or procedure that is the basis for action. Nursing theories are knowledge-based concepts that guide nurses' actions, influence nursing education and practice, and allow nurses to care for their patients.
Theories provide a perspective to assess patients' conditions and organize data and methods. They also assist in analyzing and interpreting information. They represent a...
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Equivalent Circuits for Practical Transformers01:28

Equivalent Circuits for Practical Transformers

1.4K
The practical equivalent circuits of single-phase two-winding transformers exhibit significant deviations from their idealized versions due to the inherent properties of winding resistance and finite core permeability. These properties result in real and reactive power losses, affecting the transformer's performance. Understanding these deviations is crucial for designing more efficient transformers.
In a practical transformer, each winding exhibits resistance and leakage reactance. The...
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Related Experiment Video

Updated: Jan 23, 2026

Measuring the Motor Aspect of Cancer-Related Fatigue using a Handheld Dynamometer
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Measuring the Motor Aspect of Cancer-Related Fatigue using a Handheld Dynamometer

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A Practical Approach to Fatigue Management in Colorectal Cancer.

Matti Aapro1, Florian Scotte2, Thierry Bouillet3

  • 1Multidisciplinary Oncology Institute, Clinique de Genolier, Genolier, Switzerland.

Clinical Colorectal Cancer
|October 26, 2017
PubMed
Summary
This summary is machine-generated.

Cancer-related fatigue significantly impacts colorectal cancer patients. Emerging evidence suggests exercise programs can improve fatigue, quality of life, and treatment tolerance.

Keywords:
Cancer managementCancer-related fatigueColorectal cancerExerciseQuality of life

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Area of Science:

  • Oncology
  • Clinical Medicine
  • Exercise Physiology

Background:

  • Cancer-related fatigue is a prevalent and complex symptom in colorectal cancer patients, diminishing quality of life and daily functioning.
  • Existing definitions from the European Association for Palliative Care (EAPC) and National Comprehensive Cancer Network (NCCN) highlight the lack of consensus.
  • Multiple factors, including disease progression, comorbidities, anemia, and psychological aspects, contribute to fatigue, necessitating comprehensive management strategies.

Purpose of the Study:

  • To review the current understanding of cancer-related fatigue in colorectal cancer.
  • To assess the evidence for physical activity interventions in managing this fatigue.
  • To propose updates to a treatment algorithm for clinicians managing colorectal cancer-related fatigue.

Main Methods:

  • Literature review assessing cancer-related fatigue in colorectal cancer patients.
  • Evaluation of the impact of physical activity and exercise programs on fatigue and quality of life.
  • Analysis of existing management guidelines from EAPC and NCCN.

Main Results:

  • Physical activity demonstrates beneficial physiological effects that can counteract fatigue causes.
  • Emerging evidence supports exercise programs in improving cancer-related fatigue, quality of life, and clinical outcomes in colorectal cancer patients.
  • Exercise may enhance chemotherapy tolerance.

Conclusions:

  • Physical activity is a promising intervention for managing cancer-related fatigue in colorectal cancer.
  • Updated treatment algorithms incorporating exercise are needed to optimize patient care.
  • Further research and randomized controlled trials are warranted to solidify the role of exercise in cancer-related fatigue management.