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Depression and cardiovascular disease in elderly: Current understanding

Yaxin Zhang1, Yujing Chen2, Lina Ma1

  • 1Department of Geriatrics, Xuan Wu Hospital, Capital Medical University, Beijing Institute of Geriatrics, China National Clinical Research Center for Geriatric Disorders, Beijing 100053, China.

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
|October 26, 2017
PubMed

Insights

Geriatric depression significantly impacts health, especially when combined with chronic conditions like cardiovascular disease. Understanding the link between geriatric depression and cardiovascular disease is crucial for better treatment strategies.

Area of Science:

  • Geriatric Medicine
  • Cardiology
  • Psychiatry

Background:

  • Geriatric depression is a significant public health concern.
  • Comorbidity with chronic medical conditions, such as cardiovascular disease, exacerbates health impacts.
  • Depression is a prevalent risk factor for cardiovascular disease morbidity and mortality.

Purpose of the Study:

  • To review the current understanding of geriatric depression.
  • To explore the relationship between geriatric depression and cardiovascular disease.
  • To highlight the importance of understanding pathophysiological mechanisms and biological crosstalk.

Main Methods:

  • Literature review of current evidence on geriatric depression and cardiovascular disease.
  • Analysis of the impact of comorbid depression on chronic conditions.
  • Examination of the interplay between depression and cardiovascular health.

Main Results:

  • Geriatric depression frequently co-occurs with hypertension, coronary heart disease, and diabetes.
  • Depression affects the treatment and prognosis of cardiovascular diseases.
  • Evidence on antidepressive therapy in patients with coronary diseases is limited.

Conclusions:

  • Effective management requires addressing both primary diseases and psychological/social function.
  • Further research into the pathophysiological mechanisms is vital for developing future therapeutic strategies.
  • Understanding the complex biological crosstalk is key for managing comorbid geriatric depression and cardiovascular disease.

Keywords:
Cardiovascular diseaseDepressionElderly

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