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Adverse effects with oral 5-aminosalicyclic acid
J M Fardy1, D A Lloyd, R P Reynolds
1Department of Medicine, St. Joseph's Health Centre, London, Ontario, Canada.
Journal of Clinical Gastroenterology
|December 1, 1988
Abstract:
Two patients with ulcerative colitis and a past history of allergic reactions to sulfasalazine had similar reactions when treated with 5-aminosalicylic acid. This suggests that, at least in some patients, the adverse effects of sulfasalazine are due to 5-aminosalicylic acid rather than sulfapyridine. Desensitization to sulfasalazine was successfully carried out in one patient but was not attempted in a second.