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Cell Lines

Cell Lines

A cell line is a population of cells grown in vitro that can be subcultured over several generations. Normal cells cease to divide after a certain number of cell divisions, a process known as replicative senescence. This number, called the Hayflick limit, was conceptualized by Leonard Hayflick in 1961 when he observed that fetal cells grown in culture could only divide 40-60 times. This limit is due to the shortening of the telomeres during each round of cell division, preventing cell division...

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Cell Culture Techniques and Practices to Avoid Contamination by Fungi and Bacteria in the Research Cell Culture Laboratory

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The Imperative Authentication of Cell Lines

Armando Rojas¹

¹Biomedical Research Lab., Medicine Faculty, Catholic University of Maule, Talca, Chile arojasr@ucm.cl.

Antimicrobial Agents and Chemotherapy

|October 26, 2017

Summary

No abstract available in PubMed .

Keywords:

cell line authentication cross-contamination

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