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Acute hepatitis B virus infection and severe non-immune haemolytic anaemia: a rare relationship

Inês Furtado1, Diana Valadares2, Filipe Gaio Nery2

  • 1Internal Medicine Department, Centro Hospitalar do Porto, Porto, Portugal.

BMJ Case Reports
|October 26, 2017
PubMed

The clinical presentation of acute hepatitis B virus (HBV) infection is usually related to the onset of liver failure and damage. Anaemia may occur, but it is only rarely attributed to haemolysis. The authors report about the case of a 41-year-old woman with the diagnosis of acute HBV infection and coagulopathy (without encephalopathy) who developed non-immune haemolytic anaemia. Total recovery of the analytical liver profile, coagulopathy and anaemia was achieved through treatment targeting HBV.This case shows that, although rare, non-immune haemolytic anaemia may occur in association with acute HBV infection and that HBV suppression seems to lead to progressive anaemia resolution.

Keywords:
haematology (incl blood transfusion)hepatitis and other gi infectionshepatitis binfectious diseases

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