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Updated: Feb 20, 2026

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
Published on: April 4, 2018
[Clinical Application of NGS-Based Clinical Sequencing]
1Dept. of Genome Biology, Kindai University Faculty of Medicine.
Abstract:
Cancer Clinical Sequencing is a method for making the treatment decision for each cancer patient. Implication of the clinical sequencing is rapidly in progress in Japan. In general, the tumor FFPE samples obtained by biopsy or operatory resection are subjected to amplicon sequencing. The process was divided into pre-analysis, analysis, and post-analysis processes. Quality assurance and control are necessary for all process. In addition, the expert members for clinical sequencing team is essential to make clinical sequencing reports based on the NGS analysis.
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