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Updated: Feb 20, 2026

Asthma Detection Research Based on Voice Signal Processing and Machine Learning
Published on: July 22, 2025
Differentiating vocal cord dysfunction from asthma.
Andrew Fretzayas1,2, Maria Moustaki3, Ioanna Loukou3
1Third Department of Pediatrics, Athens University Medical School, "Attikon" University Hospital, Haidari, Greece.
Vocal cord dysfunction (VCD) causes breathing issues like wheezing and shortness of breath in children, often mistaken for asthma. Accurate diagnosis is key for effective treatment.
Area of Science:
- Pediatric Pulmonology
- Laryngology
Background:
- Vocal cord dysfunction (VCD) presents with symptoms like dyspnea, wheezing, and stridor in pediatric patients.
- These symptoms, often occurring during exercise, can be misdiagnosed as asthma, especially when unresponsive to standard treatments.
Purpose of the Study:
- To highlight the importance of accurately diagnosing VCD in children.
- To differentiate VCD from asthma and guide appropriate therapeutic strategies.
Main Methods:
- Diagnosis relies on fiberoptic laryngoscopy, ideally performed during symptomatic episodes.
- Exercise challenges, including continuous laryngoscopy during exercise (treadmill, ergometer, swimming), are employed for diagnosing exercise-induced VCD.
Main Results:
- VCD symptoms can mimic asthma, leading to misdiagnosis and ineffective treatment.
- Identifying VCD is crucial for initiating correct management, distinguishing it from or alongside asthma.
Conclusions:
- Accurate diagnosis of VCD is essential for pediatric patients presenting with respiratory symptoms.
- Distinguishing VCD from asthma ensures appropriate treatment, addressing either condition alone or concurrently.
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