Behavioral factors for predicting severity of enuresis and treatment responses in different compliance groups
Yanli Ma1, Xiaomei Liu2, Ying Shen3
1Yanli Ma, Department of Nephrology, Beijing Children's Hospital, Capital Medical University, Beijing Key Laboratory of Chronic Kidney Disease andBlood Purification of Children. No.56, South Lishi Road, Xicheng District, Beijing, China.
Insights
Behavioral factors like stool frequency and fluid intake impact nocturnal enuresis severity. High compliance with behavioral interventions significantly improves treatment outcomes for bedwetting in children.
Area of Science:
- Pediatric Urology
- Behavioral Medicine
- Sleep Medicine
Background:
- Nocturnal enuresis affects a significant number of children, impacting their quality of life.
- Identifying predictive factors and optimizing treatment adherence are crucial for effective management.
Purpose of the Study:
- To identify behavioral factors predicting nocturnal enuresis severity.
- To compare treatment response rates based on compliance with behavioral interventions.
Main Methods:
- 311 children with nocturnal enuresis were studied.
- Behavioral factors and enuresis severity were correlated.
- Patients received desmopressin and behavioral interventions for two months, with compliance assessed post-treatment.
Main Results:
- Stool frequency, pre-sleep fluid intake, nighttime awakenings for toileting, and appetite were independent risk factors for enuresis severity.
- Higher compliance groups demonstrated significantly better complete and partial response rates compared to lower compliance groups (P<0.01).
Conclusions:
- Specific behavioral factors are key predictors of nocturnal enuresis severity.
- Adherence to behavioral interventions plays a critical role in achieving successful therapeutic outcomes for childhood bedwetting.
Objective:
To investigate behavioral factors for predicting severity of nocturnal enuresis and compare response rates in different compliance groups of behavioral interventions.
Methods:
Three hundred eleven children diagnosed with nocturnal enuresis were enrolled. This study was conducted at Beijing Children's Hospital affiliated to the Capital Medical University from September 2016 to December 2016. Correlation of severity of enuresis and behavioral factors was investigated. All patients were treated with desmopressin based on behavioral interventions. After twomonth treatment, the patients were grouped according to the compliance of behavioral therapy. Then response rates in different compliance groups were compared.
Results:
Multivariate analysis revealed stool frequency, drinking water before going to bed, awaking the child to toilet at night, and appetite were independent risk factors affecting the severity of enuresis. The complete response rate of enuresis and partial response ratein fullcompliance group are higher than thoseof partial compliance and non-compliance group(21.9% vs 11.3%, 78.1% vs 59.8%; 21.9% vs 0%, 78.1% vs 49.1%; P<0.01). The complete response rate and partial response rate of partial compliance group are higher than those of the non-compliance group (P<0.01).
Conclusions:
Stool frequency, drinking water before going to bed, awaking the child to toilet at night, and appetite are independent predictive factors affecting the severity of enuresis. Good compliance of behavioral interventions may have a crucial role for better therapeutic outcomes.
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