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[Somatostatin does not modify 3-oxymethylglucose and leucine uptake by rat enterocytes]
C A Crespo1, J Martínez-Sapiña, M C Taboada
1Departamento de Fisiología Facultad de Farmacia, Santiago de Compostela, España.
Abstract:
The effects of somatostatin on 3-oxymethylglucose (3-OMG) and leucine uptake by rat enterocytes were examined. Somatostatin did not decrease the 3-OMG enterocyte uptake. When the 3-OMG active transport was inhibited by phloridzin, Somatostatin presented no significant modifications. Somatostatin showed a slight decrease in 3-OMG release through the basolateral membrane, when such a release was inhibited with theophylline. Somatostatin did not modify the intestinal leucine uptake or its inhibition by methionine.