Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Endocarditis I: Introduction01:25

Endocarditis I: Introduction

558
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
558
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

589
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
589
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

964
Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
964
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

14.0K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
14.0K
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

420
Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
420
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

271
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
271

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Canadian Surgery Forum.

Canadian journal of surgery. Journal canadien de chirurgie·2022
Same author

Correction to: A 3i hip fracture liaison service with nurse and physician co-management is cost-effective when implemented as a standard clinical program.

Archives of osteoporosis·2020
Same author

A 3i hip fracture liaison service with nurse and physician co-management is cost-effective when implemented as a standard clinical program.

Archives of osteoporosis·2020
Same author

Implementation of an in-patient hip fracture liaison services to improve initiation of osteoporosis medication use within 1-year of hip fracture: a population-based time series analysis using the RE-AIM framework.

Archives of osteoporosis·2020
Same author

Increase in ST-11 serogroup W <i>Neisseria meningitidis</i> invasive meningococcal disease in Canada, 2016-2018.

Canada communicable disease report = Releve des maladies transmissibles au Canada·2019
Same author

Factors associated with pneumococcal vaccination in 2040 people with type 2 diabetes: A cross-sectional study.

Diabetes & metabolism·2019
Same journal

Consensus-based evaluation of RIDASCREEN<sup>®</sup> TB ELISA compared with two interferon-gamma release assays in a low-incidence setting.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology·2026
Same journal

A review of bloodstream infections-pathogens, pathogenesis, diagnostic strategies, treatment methods-challenges and future aspects.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology·2026
Same journal

Adaptive susceptibility shifts in Candidozyma auris following biocidal exposure: Exploratory effects on antifungal and biocidal susceptibility.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology·2026
Same journal

Prevalence and risk factors of sexually transmitted infections in women in eleven hospitals in two low-income countries: a cross-sectional study.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology·2026
Same journal

Tetracycline for Helicobacter pylori eradication: a narrative review from quadruple to dual therapy.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology·2026
Same journal

Breaking barriers: Implementation of a tuberculosis preventive treatment protocol among newly eligible populations with promising results.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology·2026
See all related articles

Related Experiment Video

Updated: Feb 20, 2026

Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling
08:25

Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling

Published on: April 7, 2015

9.5K

Risk factors for pneumococcal endocarditis.

T J Marrie1, G J Tyrrell2, S R Majumdar3

  • 1Department of Medicine, Dalhousie University, Halifax, NS, Canada.

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology
|October 26, 2017
PubMed
Summary
This summary is machine-generated.

Infective endocarditis is a rare but serious complication of invasive pneumococcal disease (IPD). While illicit drug use is a risk factor, endocarditis significantly increases mortality in IPD patients.

More Related Videos

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
11:32

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria

Published on: February 23, 2014

15.7K
Pneumococcus Infection of Primary Human Endothelial Cells in Constant Flow
09:34

Pneumococcus Infection of Primary Human Endothelial Cells in Constant Flow

Published on: October 31, 2019

7.0K

Related Experiment Videos

Last Updated: Feb 20, 2026

Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling
08:25

Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling

Published on: April 7, 2015

9.5K
Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
11:32

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria

Published on: February 23, 2014

15.7K
Pneumococcus Infection of Primary Human Endothelial Cells in Constant Flow
09:34

Pneumococcus Infection of Primary Human Endothelial Cells in Constant Flow

Published on: October 31, 2019

7.0K

Area of Science:

  • Infectious Diseases
  • Cardiology
  • Public Health

Background:

  • Bacteremia is a common presentation of invasive pneumococcal disease (IPD).
  • Endocarditis is a known complication of bacteremia, but its incidence and risk factors in IPD are understudied.
  • This study addresses the need for data on IPD-associated endocarditis.

Purpose of the Study:

  • To determine the incidence of endocarditis in a large cohort of adult IPD patients.
  • To identify sociodemographic and clinical risk factors associated with IPD-related endocarditis.
  • To compare outcomes, including mortality, between IPD patients with and without endocarditis.

Main Methods:

  • Prospective collection of all invasive pneumococcal disease (IPD) cases in Northern Alberta, Canada, from 2000 to 2014.
  • Descriptive statistical analysis comparing patients with and without endocarditis.
  • Evaluation of sociodemographic variables, clinical characteristics, and IPD-related outcomes.

Main Results:

  • Endocarditis occurred in 0.3% (28/3251) of adult IPD patients.
  • Endocarditis patients had higher rates of illicit drug use, altered mental status, and intensive care unit (ICU) admission (p < 0.05).
  • New murmur development (39.3% vs 2.2%, p < 0.001) and mortality (39.3% vs 14.7%) were significantly higher in endocarditis patients. No pneumococcal serotype predilection was observed.

Conclusions:

  • Infective endocarditis is an uncommon but significant complication of invasive pneumococcal disease (IPD).
  • Illicit drug use emerged as a key risk factor for IPD-related endocarditis.
  • Endocarditis is associated with substantially increased mortality in IPD patients, underscoring the need for vigilance and early detection.