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Related Concept Videos

Other Pulmonary Disorders01:17

Other Pulmonary Disorders

1.7K
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
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COPD: Pathogenesis and Clinical Features01:20

COPD: Pathogenesis and Clinical Features

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Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
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Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

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Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
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Pulmonary Hypertension: Classification and Pathogenesis01:30

Pulmonary Hypertension: Classification and Pathogenesis

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Pulmonary hypertension (PH) is a severe health condition in which the mean pulmonary arterial pressure increases to 25 mmHg or more, even when the body is at rest. This high pressure in the blood vessels that transport blood from the heart to the lungs can cause various symptoms, including shortness of breath, can lead to right heart failure, and significantly affect the overall quality of life.
There are various classifications for PH, each relating to different underlying causes and also...
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Fungal Phylum Ascomycota01:28

Fungal Phylum Ascomycota

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Phylum Ascomycota, a major division within the subkingdom Dikarya, comprises a diverse range of fungal species, including both unicellular yeasts and filamentous molds such as Aspergillus and Penicillium. These fungi thrive in a variety of habitats, from aquatic ecosystems to terrestrial environments, playing crucial ecological and economic roles.Morphology and ReproductionThe defining characteristic of Ascomycetes, commonly referred to as sac fungi, is the ascus—a sac-like structure that...
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Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.01:25

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

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Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
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Related Experiment Video

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Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis
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Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis

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Pulmonary Aspergillus Overlap Syndromes.

Liyang Li1, Zhilong Jiang1, Changzhou Shao2

  • 1Department of Pulmonary Medicine, Shanghai Respiratory Research Institute, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.

Mycopathologia
|October 26, 2017
PubMed
Summary
This summary is machine-generated.

Aspergillus overlap syndromes (AOS) present with varied symptoms, complicating diagnosis and treatment. Early awareness and appropriate therapy are crucial for managing these complex pulmonary aspergillosis cases.

Keywords:
Allergic bronchopulmonary aspergillosisAspergillomaAspergillus overlap syndromesInvasive pulmonary aspergillosis

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Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow Technology
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Area of Science:

  • Pulmonology
  • Infectious Diseases
  • Mycology

Background:

  • Pulmonary aspergillosis encompasses chronic forms, allergic bronchopulmonary aspergillosis (ABPA), and invasive aspergillosis (IPA).
  • IPA is subcategorized into angioinvasive and airway-invasive forms.
  • Aspergillus overlap syndromes (AOS) involve concurrent presentations of multiple aspergillosis forms in a single patient.

Purpose of the Study:

  • To guide clinicians in the accurate diagnosis and management of AOS.
  • To elucidate the clinical characteristics of patients with AOS.

Main Methods:

  • Retrospective analysis of clinical data from nine patients diagnosed with AOS.
  • Review of patient presentations, diagnostic findings, and treatment outcomes.

Main Results:

  • Diverse AOS presentations included angioinvasive aspergillosis with ABPA, IPA overlap aspergilloma, and ABPA with airway-invasive aspergillosis.
  • Common symptoms were cough and expectoration; hemoptysis, wheezing, and fever were also noted.
  • Treatment involved steroids and antifungals, with most patients showing improvement, except for one case of ABPA overlap IPA.

Conclusions:

  • AOS often lacks typical clinical manifestations, posing diagnostic challenges.
  • Suboptimal responses to initial therapies and complex diagnostic criteria necessitate heightened clinical suspicion for AOS.
  • Prompt recognition and tailored treatment strategies are essential for improving outcomes in patients with aspergillosis overlap syndromes.