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Optimization of Surgical Outcome in Lower Extremity Nerve Decompression Surgery
Willem D Rinkel1,2, Jasper L de Kleijn1,2, Joanne F M Macaré van Maurik1,2
1Rotterdam, Utrecht, and Tiel, The Netherlands.
Plastic and Reconstructive Surgery
|October 26, 2017
Summary
Surgical nerve decompression in the lower extremities offers benefits for select patients. Factors like preoperative nerve damage and diabetes duration influence surgical outcomes for neuropathy relief.
Area of Science:
- Neurology
- Diabetic Complications
- Surgical Outcomes
Background:
- Debate exists on the efficacy of surgical nerve release for lower extremity neuropathy.
- Factors influencing positive surgical outcomes require further investigation.
Purpose of the Study:
- To identify factors associated with favorable surgical outcomes in lower extremity nerve entrapment.
- To evaluate long-term (5-year) outcomes of diabetic patients from a randomized controlled trial.
Main Methods:
- Follow-up of diabetic patients from the Lower Extremity Nerve Entrapment Study (LENS).
- Assessment of pain, quality of life, sensory function, and complication rates.
- Comparison of unilateral versus bilateral surgical decompression outcomes.
Main Results:
- Bilateral decompression was associated with lower pain and better quality of life compared to unilateral decompression.
- Younger patients with earlier diabetes diagnosis and lower BMI showed better outcomes.
- Severe preoperative sensory loss correlated with poorer outcomes.
Conclusions:
- Lower extremity nerve decompression surgery benefits a specific patient group.
- Preoperative nerve damage, age, diabetes duration, and BMI are key factors influencing outcomes.

