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Updated: Feb 20, 2026

Assessment of Memory Function in Pilocarpine-induced Epileptic Mice
Published on: June 4, 2020
Accelerated Long-Term Forgetting Limited to the Recollection Component of Recognition Memory in a Temporal Lobe
Giovanni Augusto Carlesimo1,2, Antonio Daniele3, Maria Giovanna Lombardi2
1a Department of Systems Medicine , "Tor Vergata" University , Rome , Italy.
Abstract:
Accelerated long-term forgetting (ALF) is a frequent finding in patients with temporal lobe epilepsy (TLE). Here we report the case of a TLE patient who complained of marked difficulties in remembering personal events and information even though repeated neuropsychological assessments had failed to detect any deficit on common laboratory memory tests. The patient underwent an experimental investigation that involved estimating recollection and familiarity processes in the performance on verbal and visual recognition tests, over intervals ranging from 10 minutes to 7 days. Results showed accelerated forgetting confined to the recollection component only, which was particularly evident in the verbal test.
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