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Does egg donation for mitochondrial replacement techniques generate parental responsibilities?

César Palacios-González

    Journal of Medical Ethics
    |October 27, 2017
    PubMed
    Summary
    This summary is machine-generated.

    Mitochondrial replacement techniques (MRTs) create children with DNA from three individuals. This paper argues that, in certain situations, egg donors in MRT procedures bear parental responsibilities for the resulting children.

    Keywords:
    gene therapy/transferreproductive medicine

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    Area of Science:

    • Bioethics
    • Reproductive Science
    • Genetics

    Background:

    • Mitochondrial replacement techniques (MRTs) involve nuclear DNA from two parents and mitochondrial DNA from a donor.
    • This genetic composition raises questions about the number of genetic parents and parental responsibilities.

    Purpose of the Study:

    • To determine if mitochondrial replacement technique (MRT) egg donors have parental responsibilities.
    • To explore the implications for the number of genetic parents involved in MRT procedures.

    Main Methods:

    • Review of mitochondrial diseases and MRTs.
    • Analysis of the numerical identity of eggs and zygotes in MRTs.
    • Examination of genetic and causal accounts of parenthood in the context of MRT egg donation.

    Main Results:

    • MRT procedures result in children with genetic material from three individuals.
    • Both genetic and causal accounts of parenthood can attribute responsibility to MRT egg donors.

    Conclusions:

    • Under specific circumstances, MRT egg donors can be considered parentally responsible for children conceived via MRT.
    • The study clarifies the parental status of egg donors in assisted reproductive technologies.