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Ciliary Body Mesectodermal Leiomyoma Diagnosed by Fine Needle Aspiration Biopsy
Hayyam Kiratli1, Abdullah Ağın1, Sevgen Önder2
1Ocular Oncology Service, Department of Ophthalmology, Hacettepe University, School of Medicine, Ankara, Turkey.
Ocular Oncology and Pathology
|October 27, 2017
Summary
Mesectodermal leiomyoma of the ciliary body was diagnosed using fine needle aspiration biopsy. Stereotactic radiotherapy effectively reduced tumor size by 40% over 5 years.
Area of Science:
- Ophthalmology
- Oncology
- Pathology
Background:
- Mesectodermal leiomyoma is a rare tumor.
- Ciliary body tumors require accurate diagnosis for appropriate management.
- Fine needle aspiration biopsy (FNAB) offers a minimally invasive diagnostic approach.
Purpose of the Study:
- To detail the diagnostic features of ciliary body mesectodermal leiomyoma via FNAB.
- To evaluate the efficacy of stereotactic radiotherapy for this tumor.
Main Methods:
- Retrospective review of clinical, imaging, and cytopathological data.
- Fine needle aspiration biopsy with 25-G needle and scleral flap.
- Immunohistochemical analysis of tumor cells.
Main Results:
- FNAB revealed cells with granular cytoplasm and large nuclei.
- Immunohistochemistry showed positive staining for smooth muscle actin, desmin, h-caldesmon, CD56, and neuron-specific enolase.
- Fractionated stereotactic radiotherapy resulted in a 40% tumor size reduction over 5 years.
Conclusions:
- FNAB is a viable method for diagnosing mesectodermal leiomyoma of the ciliary body.
- Stereotactic radiotherapy can be an effective treatment for inducing tumor regression.
