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Nutrient drink test: Normative values in Indian children.

Upender Shava1, Anshu Srivastava2, Amrita Mathias1

  • 1Department of Pediatric Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, 226 014, India.

Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology
|October 27, 2017
PubMed
Summary

This study establishes normal satiety drink volumes (SDV) and postprandial symptoms (PPS) in children using the nutrient drink test (NDT). SDV correlates with age and is higher in adolescent boys, providing crucial normative data.

Keywords:
ChildrenFunctional dyspepsiaGastric accommodationNormal valuesNutrient drink test

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Area of Science:

  • Pediatric Gastroenterology
  • Digestive Physiology

Background:

  • The nutrient drink test (NDT) assesses gastric function, but normal satiety drink volume (SDV) and postprandial symptoms (PPS) data in children are limited.
  • Establishing normative values is essential for clinical interpretation of NDT in pediatric populations.

Purpose of the Study:

  • To establish normal SDV and PPS values in healthy children aged 6-18 years using NDT.
  • To investigate the correlation of SDV with age, gender, and anthropometric measurements.
  • To characterize postprandial symptoms experienced by children during the NDT.

Main Methods:

  • Healthy children aged 6-18 years underwent NDT with a standardized nutrient drink.
  • Drink infusion rates varied by age group (15 mL/min for 6-12 years, 30 mL/min for 13-18 years) until a satiety score of 5 was reached.
  • Postprandial symptoms (fullness, nausea, bloating, pain) were assessed using a visual analog scale 30 minutes after the test.

Main Results:

  • Sixty-seven children were enrolled; median SDV was 360 mL, significantly higher in 13-18-year-olds compared to 6-12-year-olds (p=0.005).
  • SDV positively correlated with age, weight, and height.
  • SDV was higher in adolescent boys than girls (p=0.02), while PPS were mild and not significantly different between groups.

Conclusions:

  • This study provides the first normative data for SDV and PPS in children aged 6-18 years using NDT.
  • SDV is influenced by age and gender, with adolescent boys exhibiting higher volumes.
  • The findings aid in the clinical assessment of gastric function in pediatric patients.