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[Diagnostic value of high-field MRI for Peyronie's disease]
Huan-Jun Wang1, Jian Guan2, Jin-Hua Lin2
1Department of Radiology, The First Hospital Affiliated to Sun Yat-sen University, Guangzhou, Guangdong 510080, China.
Objective:
To analyze the MRI manifestations of Peyronie's disease and investigate the value of high-field MRI in the diagnosis of the disease.
Methods:
Using a small surface coil, we performed 3.0 Tesla MRI for 14 patients with clinically diagnosed Peyronie's disease. The MRI protocol included routine sequences (T1WI, T2WI, and enhanced T1WI) and susceptibility-weighted imaging (SWI). Each patient had received 2－4 penile ultrasound examinations previously. We compared the MRI findings with the results of ultrasonography.
Results:
MRI manifested 25 penile plaques in the 14 patients, 3 (7 plaques) with inflammation, 4 (8 plaques) with fibrosis, and the other 7 (10 plaques) with calcification displaying a low signal intensity on SWI. Ultrasonography had revealed the 10 calcified plaques in all the 20 examinations, but exhibited the 7 inflammatory and 8 fibrotic ones in only 3 of the 23 examinations. The combination of MRI SWI sequences was necessitated for the detection of calcified plaques and achieved higher detection rates than ultrasonography for inflammatory and fibrotic plaques (P<0.05).
Conclusions:
High-field MRI has high sensitivity and accuracy in the diagnosis of Peyronie's disease, which can effectively display penile plaques of different nature in the early stage through multi-parametric sequences.
Insights
High-field MRI effectively diagnoses Peyronie's disease by identifying penile plaques. Susceptibility-weighted imaging (SWI) enhances detection of calcified, fibrotic, and inflammatory plaques compared to ultrasound.
Area of Science:
- Radiology
- Urology
- Medical Imaging
Background:
- Peyronie's disease is characterized by penile plaque formation.
- Accurate diagnosis is crucial for effective treatment planning.
Purpose of the Study:
- To evaluate the diagnostic value of high-field MRI in Peyronie's disease.
- To analyze MRI manifestations of penile plaques.
Main Methods:
- 14 patients with Peyronie's disease underwent 3.0 Tesla MRI with routine sequences and SWI.
- MRI findings were compared with previous penile ultrasound examinations.
Main Results:
- MRI detected 25 penile plaques, classifying them as inflammatory, fibrotic, or calcified.
- MRI, particularly SWI, showed higher detection rates for inflammatory and fibrotic plaques than ultrasound.
- SWI was crucial for detecting calcified plaques.
Conclusions:
- High-field MRI demonstrates high sensitivity and accuracy for diagnosing Peyronie's disease.
- Multi-parametric MRI sequences effectively visualize penile plaques in early stages.
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