Third cranial nerve palsy: an unusual manifestation of Mycoplasma pneumoniae

Dalia Nelson1, Heather Angus-Leppan2, Phillip Jacobs3

  • 1MBBS, BSc (hons), Barnet Hospital Education Centre, Wellhouse Lane, Barnet EN5 3DJ.

Acute Medicine
|October 27, 2017
PubMed

Insights

Mycoplasma pneumoniae causes atypical pneumonia and can lead to various extrapulmonary issues. This case study details a patient experiencing gastrointestinal, blood, and neurological complications, including third cranial nerve palsy, post-treatment.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Internal Medicine

Background:

  • Mycoplasma pneumoniae is a common pathogen responsible for atypical pneumonia.
  • Beyond respiratory infections, M. pneumoniae is increasingly recognized for causing diverse extrapulmonary manifestations.
  • Understanding these extrapulmonary complications is crucial for comprehensive patient management.

Purpose of the Study:

  • To report a unique case of Mycoplasma pneumoniae infection with multiple extrapulmonary complications.
  • To highlight the neurological sequelae, specifically third cranial nerve palsy, occurring after initial treatment.
  • To emphasize the importance of considering M. pneumoniae in patients presenting with unusual systemic symptoms.

Main Methods:

  • Case report detailing a patient's clinical presentation, diagnostic workup, and treatment course.
  • Review of relevant medical literature on Mycoplasma pneumoniae and its extrapulmonary manifestations.
  • Clinical observation and follow-up of the patient's recovery and neurological status.

Main Results:

  • The patient presented with symptoms indicative of atypical pneumonia.
  • Following initial treatment, the patient developed significant gastroenterological, haematological, and neurological complications.
  • A notable complication was the development of a third cranial nerve palsy.

Conclusions:

  • Mycoplasma pneumoniae can present with a wide spectrum of extrapulmonary manifestations.
  • Neurological complications, such as cranial nerve palsies, can occur late in the disease course or post-treatment.
  • This case underscores the need for vigilance in diagnosing and managing M. pneumoniae infections, considering its potential for systemic involvement.

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