Multielectron, multisubstrate molecular catalysis of electrochemical reactions: Formal kinetic analysis in the total catalysis regime
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Updated: Feb 20, 2026

Multiscale Sampling of a Heterogeneous Water/Metal Catalyst Interface using Density Functional Theory and Force-Field Molecular Dynamics
Published on: April 12, 2019
Cyrille Costentin1, Daniel G Nocera2, Casey N Brodsky3
1Laboratoire d'Electrochimie Moléculaire, Unité Mixte de Recherche Université-CNRS No.7591, Université Paris Diderot, Sorbonne Paris Cité, 75205 Paris Cedex 13, France; dnocera@fas.harvard.edu cyrille.costentin@univ-paris-diderot.fr.
Abstract:
Cyclic voltammetry responses are derived for two-electron, two-step homogeneous electrocatalytic reactions in the total catalysis regime. The models developed provide a framework for extracting kinetic information from cyclic voltammograms (CVs) obtained in conditions under which the substrate or cosubstrate is consumed in a multielectron redox process, as is particularly prevalent for very active catalysts that promote energy conversion reactions. Such determination of rate constants in the total catalysis regime is a prerequisite for the rational benchmarking of molecular electrocatalysts that promote multielectron conversions of small-molecule reactants. The present analysis is illustrated with experimental systems encompassing various limiting behaviors.
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