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Sleep apnea severity and depressive symptoms in a population-based study
Annemarie I Luik1, Jenna Noteboom1, Lisette A Zuurbier1
1Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands.
Sleep Health
|October 27, 2017
Summary
Sleep apnea severity is not consistently linked to depression in the general population. However, some men with moderate sleep apnea showed increased depressive symptoms.
Area of Science:
- Epidemiology
- Sleep Medicine
- Psychiatry
Background:
- Sleep apnea and depression frequently co-occur, but population-based evidence remains inconsistent.
- Understanding this relationship is crucial for public health and clinical practice.
Purpose of the Study:
- To investigate the association between sleep apnea severity and depressive symptoms in a population-based sample.
- To explore potential sex differences in this association.
Main Methods:
- Cross-sectional cohort study of 491 middle-aged and elderly individuals from the Rotterdam Study.
- Sleep apnea severity was quantified using the apnea hypopnea index (AHI) via polysomnography.
- Depressive symptoms were assessed using the Center for Epidemiologic Studies Depression Scale.
Main Results:
- No significant association was found between overall sleep apnea severity and depressive symptoms in the total sample.
- A curvilinear association was observed in men, with moderate AHI levels (5-15 and 15-30) linked to higher depressive symptoms compared to severe AHI (≥30).
Conclusions:
- Sleep apnea severity does not consistently correlate with depressive symptoms in a population-based setting.
- An association between sleep apnea severity and depressive symptoms was suggested specifically in men with moderate sleep apnea.
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