Related Experiment Video
Updated: Feb 20, 2026
05:31
Transradial Access Chemoembolization for Hepatocellular Carcinoma Patients
Published on: September 20, 2020
6.2K
Bronchial artery embolization: first-line option for managing massive hemoptysis
Yutaka Miyano1,2, Masato Kanzaki1, Takamasa Onuki3
11 Department of Surgery I, Tokyo Women's Medical University, Tokyo, Japan.
Asian Cardiovascular & Thoracic Annals
|October 28, 2017
Summary
Bronchial artery embolization is a safe and effective first-line treatment for massive hemoptysis, regardless of the cause. Bronchial occlusion offers emergency hemostasis but requires further treatment.
Area of Science:
- Interventional Pulmonology
- Thoracic Surgery
- Vascular Interventions
Background:
- Hemoptysis management traditionally involves surgery, but less invasive options are now available.
- Bronchial artery embolization (BAE) is recognized as an effective treatment for hemoptysis.
Purpose of the Study:
- To evaluate the safety and effectiveness of bronchial artery embolization (BAE) for massive hemoptysis.
- To compare BAE with bronchial occlusion in managing hemoptysis.
Main Methods:
- Retrospective study of 389 patients with massive hemoptysis.
- 179 patients were treated with BAE, irrespective of underlying pathology (e.g., bronchiectasis, lung cancer, tuberculosis).
- Comparison of outcomes between BAE and bronchial occlusion.
Main Results:
- BAE was successful in 167 out of 179 patients (93.3%).
- 16 patients required surgery after BAE; 4 underwent bronchial occlusion.
- 3 deaths occurred due to recurrent massive hemoptysis.
- BAE was effective in patients with a history of chest surgery.
- Bronchial occlusion achieved immediate hemostasis in 4 patients.
Conclusions:
- Bronchial artery embolization is a safe, minimally invasive, and repeatable treatment for hemoptysis.
- BAE provides both short-term and prolonged effectiveness, suitable as a first-line therapy.
- Bronchial occlusion is useful for emergency hemostasis but may require subsequent elective treatment like BAE.
Related Concept Videos
01:29Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
517
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
517
01:29Pulmonary Embolism I: Introduction
912
Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
912
01:18Treatment for Pulmonary Arterial Hypertension: Endothelin Receptor Antagonists
494
Endothelins (ETs) are potent vasoactive peptides critical in the human body's various physiological and pathological processes. One of the most promising therapeutic strategies for treating pulmonary arterial hypertension (PAH) involves counteracting the effects of these endothelins using a class of drugs known as endothelin receptor antagonists.
ETs are synthesized through a complex sequence of enzymatic steps, primarily involving an enzyme referred to as endothelin-converting enzyme...
ETs are synthesized through a complex sequence of enzymatic steps, primarily involving an enzyme referred to as endothelin-converting enzyme...
494
01:27Pulmonary Embolism III: Nursing Management
483
A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...
483
01:26Treatment for Pulmonary Arterial Hypertension: Receptor Tyrosine Kinase Inhibitors and Calcium Channel Blockers
573
Receptor tyrosine kinase inhibitors (TKIs) and calcium channel blockers (CCBs) are two critical categories of drugs employed in the treatment of pulmonary artery hypertension (PAH). PAH is a disease that causes high blood pressure in the pulmonary arteries, resulting in chest pain, fatigue, and shortness of breath.
TKIs, such as imatinib (Gleevec), are particularly effective in tackling the growth and mitogenic factors that become upregulated in PAH patients. These factors contribute to the...
TKIs, such as imatinib (Gleevec), are particularly effective in tackling the growth and mitogenic factors that become upregulated in PAH patients. These factors contribute to the...
573
01:23Treatment for Pulmonary Arterial Hypertension: Prostacyclin Receptor Agonists
531
Prostacyclin receptor agonists are a class of therapeutic agents integral to managing pulmonary arterial hypertension (PAH). These drugs operate by mimicking the action of prostaglandin I2, or PGI2, a naturally occurring compound in the body.
These agonists bind to the IPR receptor situated on the plasma membrane of the pulmonary artery smooth muscle cells. This binding triggers a cascade of reactions known as the GS-AC-cAMP-PKA pathway. This pathway results in the relaxation of smooth muscle...
These agonists bind to the IPR receptor situated on the plasma membrane of the pulmonary artery smooth muscle cells. This binding triggers a cascade of reactions known as the GS-AC-cAMP-PKA pathway. This pathway results in the relaxation of smooth muscle...
531