Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Feasibility and oncologic outcomes of minimally invasive surgery after induction chemoimmunotherapy for non-small cell lung cancer.

JTCVS open·2026
Same author

Targeted Molecular Profiling of Circulating Cell-Free DNA in Patients With Gastroesophageal Adenocarcinoma.

JCO precision oncology·2026
Same author

Utilization of invasive mediastinal nodal staging and prevalence of occult nodal disease in patients with synchronous primary lung cancers.

Lung cancer (Amsterdam, Netherlands)·2026
Same author

The role of diagnostic laparoscopy in staging distal esophageal adenocarcinoma.

JTCVS open·2025
Same author

Resectable non-small cell lung cancer in women: A disease-specific entity?

JTCVS open·2025
Same author

Risk and Outcomes of Secondary Cancer Among Lung Cancer Survivors After Definitive Treatment.

JAMA network open·2025

Related Experiment Video

Updated: Feb 20, 2026

A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing Neoadjuvant Therapies
07:15

A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing Neoadjuvant Therapies

Published on: July 28, 2020

10.4K

Is Repeat Pulmonary Metastasectomy Indicated for Soft Tissue Sarcoma?

Neel P Chudgar1, Murray F Brennan1, Kay See Tan2

  • 1Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.

The Annals of Thoracic Surgery
|October 28, 2017
PubMed
Summary

Repeat pulmonary metastasectomy (PM) for soft tissue sarcoma (STS) recurrence is associated with prolonged survival. Selection criteria include younger age, minimally invasive surgery, longer disease-free interval, no extrapulmonary disease, and fewer nodules.

More Related Videos

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer
04:04

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer

Published on: February 12, 2017

11.1K
Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma
07:55

Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma

Published on: April 11, 2018

15.3K

Related Experiment Videos

Last Updated: Feb 20, 2026

A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing Neoadjuvant Therapies
07:15

A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing Neoadjuvant Therapies

Published on: July 28, 2020

10.4K
Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer
04:04

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer

Published on: February 12, 2017

11.1K
Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma
07:55

Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma

Published on: April 11, 2018

15.3K

Area of Science:

  • Surgical Oncology
  • Thoracic Surgery
  • Sarcoma Research

Background:

  • Pulmonary recurrence is common after initial pulmonary metastasectomy (PM) for soft tissue sarcoma (STS).
  • Repeat PM is frequently performed, but selection criteria and survival outcomes require further definition.

Purpose of the Study:

  • To define selection criteria for repeat PM in patients with recurrent STS.
  • To identify factors associated with survival after repeat PM.

Main Methods:

  • Review of a prospectively maintained database of 539 patients undergoing PM for STS.
  • Multivariable Cox models and propensity score-matching were used to identify factors for operative selection and survival.
  • Kaplan-Meier method estimated overall survival between repeat and non-repeat PM groups.

Main Results:

  • 63% of patients experienced pulmonary recurrence, with 41% undergoing repeat PM.
  • Younger age, minimally invasive first PM, longer disease-free interval, absence of extrapulmonary disease, and fewer recurrence nodules predicted repeat PM.
  • Repeat PM was associated with improved survival; preoperative chemotherapy and incomplete resection (R1/R2) worsened survival after repeat PM.

Conclusions:

  • Repeat PM for STS is independently associated with prolonged overall survival when prognostic factors are considered.
  • Careful patient selection is crucial for optimizing outcomes after repeat PM for recurrent STS.